The order of operations is to aviate, navigate and communicate. Get the aircraft flying straight and level. If you can turn on the auto pilot to maintain altitude and heading - that frees up workload to get on the radio and issue a "mayday" to get further assistance. If you have fuel, then you have time. Time is your friend so long as you can keep the aircraft in the air.
Someone who plays FlightSim a lot will have a better chance of getting the plane on the ground than someone who has no flight experience at all. Doesn't mean the plane will land without a scratch... and it probably won't be the smoothest landing... but you have a better chance than no chance at all. So long as the plane is in good mechanical condition with enough fuel to spend time getting accustomed to the aircraft and to find a runway with a lot of room to land - you will have better odds than a cockpit with two incapacitated pilots - or someone who has no idea what to do. It's probable the landing may not be a good one and you're looking at a total loss with fatalities. But it's still a fighting chance.
Forget about the terrorists... let's focus on the two morons in the cockpit who are to blame for the majority of all airline disasters.
http://airlinesafety.com/editorials/HumanErrorVsTerrorism.htm
